For laboratory research use only. Not for human or veterinary use.Lab research use only. Not for human or animal use.

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MOTS-C 10 mg
$89.99
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Buy MOTS-C 10 mg in Australia

MOTS-C 10 mg is a research-grade peptide that is studied in cellular energy research, supplied in Australia by Australian Research Peptides to laboratories and researchers. It is the smaller of two strengths ARP lists. The 10 mg vial is independently lab-tested; no certificate is published for it yet. MOTS-C is a 16-amino-acid peptide coded inside mitochondria, the cell's energy-making parts. This 10 mg vial costs A$89.99 and is out of stock today; the 40 mg vial (A$149.99) is in stock, dispatched the same business day when paid before 12pm Sydney time. For in vitro research purposes only.

Mitochondrial Research · Lyophilised Powder · Independently lab-tested · SKU 16172
Out of stock·
$89.99

MOTS-C 10 mg is sold out for now. Leave your email and ARP will send you one email the day it is back. Nothing else.

Presentation
10 mg per vial
Grade
Research Grade
Form
Lyophilised Powder
Category
Mitochondrial Research
This strength is not in stock — stocked lines dispatch same business day before 12pm Sydney time, Mon–Fri
Tracked shipping Australia-wide · typically 1–2 business days to most areas by Express Post · free post over $199, free Express over $299
Batch certificates — published in the COA library
For in vitro research purposes only. Not for human consumption. Not for animal consumption. This product is not a drug, food, cosmetic, or dietary supplement. No medical, therapeutic, or usage information is provided.

About MOTS-C 10 mg

MOTS-C's 16-amino-acid chain is coded by mitochondrial DNA rather than the nucleus, and is studied in energy-metabolism research involving the AMPK signalling pathway. This is the 10 mg MOTS-C vial, the smaller of two, listed as 16172.

No certificate is published for this size yet. MOTS-C lots are independently lab-tested before release and the document follows.

In vitro energy metabolism research purposes only. Australian Research Peptides does not supply MOTS-C for human or veterinary use.

MOTS-C is studied in energy-metabolism research, meaning how cells make and spend energy. Published work in mice and in cell cultures reports that it switches on AMPK, a protein that senses when a cell is short of fuel. This page covers the research field and what was measured, and reports no outcome in a person.

MOTS-C is coded by a short stretch of the 12S ribosomal RNA gene, which sits in mitochondrial DNA rather than in the nucleus. Peptides coded this way are called mitochondrial-derived peptides. Humanin was the first of the group to be described, and MOTS-C came after it. The name is written and searched as MOTS-C, MOTSc and MOTS C.

Lee and colleagues first described MOTS-C in 2015 in Cell Metabolism. They identified the reading frame it comes from and tested it against the AMPK signalling pathway in cells and in mice. Australian Research Peptides reports that this published record exists and makes no claim about the material in its own vials.

Australian Research Peptides lists MOTS-C in Australia in two strengths, 10 mg and 40 mg vials of freeze-dried powder, each sealed in tamper-evident glass. People also search for it as motsc and as a mitochondrial peptide. Orders are posted from within Australia to every state and territory, so none waits on an overseas shipment. Each lot is independently lab-tested, and the CoA library shows which MOTS-C strengths have a published certificate.

BAC water (bacteriostatic water) is also in our range.

MOTS-C 10 mg specifications, storage and shipping

  • Compound: MOTS-C
  • Quantity: 10 mg
  • SKU: 16172
  • Presentation: sealed glass vial
  • Form: Lyophilised Powder
  • Grade: Research grade
  • Testing: Independently lab-tested before release
  • Identity confirmation: Mass spectrometry
  • Certificates: issued by Janoshik, an independent laboratory, and published in the COA library
  • Classification: In vitro research purposes only — laboratory reference material

Lyophilised — long term
−20 °C to −80 °C — long-term storage
Lyophilised — short term
2–8 °C — refrigerated, for a few months
Reconstituted
2–8 °C — use within 8–12 weeks
Protect from light and moisture. Handle in accordance with standard laboratory safety practice, including appropriate PPE. This information is provided for laboratory handling only and is not a usage instruction of any kind.

MOTS-C is independently lab-tested before release. No laboratory report is published for this strength yet. The COA library lists every product and strength, and says which reports are available.

This strength is not in stock today. Stocked lines ordered before 12pm Sydney time on a business day are dispatched the same day with tracked shipping. Standard delivery within Australia typically takes 2–5 business days. See Shipping & Delivery for details, and follow your parcel on the Track Order page.

For in vitro research purposes only. Not for human consumption. Not for animal consumption. Not a drug, food, cosmetic, or dietary supplement. No therapeutic or medical claims are made.

Questions about MOTS-C 10 mg

This MOTS-C 10 mg question guide from Australian Research Peptides covers the 10 mg listing on its own: its live price and stock, how it compares with the 40 mg vial, handling and storage, testing, and the MOTS-C background it shares with the larger vial. Start with the quick answers or open the topic you need.

Quick answers

Australian Research Peptides (ARP) sells MOTS-C 10 mg in Australia under 16172, at $89.99. Standard tracked post and Express Post carry MOTS-C 10 mg to all states and territories.

The 10 mg MOTS-C vial holds ten milligrams of the freeze-dried peptide, a quarter of what the 40 mg vial holds, sealed by Australian Research Peptides with no water or filler added. The label figure is the weight of dry MOTS-C in the glass; the liquid a laboratory adds later sets the strength of the solution.

MOTS-C's 40 mg vial is $149.99, $60.00 more than this 10 mg MOTS-C one. Four of these cost $359.96, so the bigger vial saves $209.97.

The 10 mg MOTS-C vial suits a small trial run or a short series of experiments, where opening a 40 mg vial would leave most of it standing as mixed solution. Ten milligrams gives the same dilute solution as the 40 mg in a quarter of the liquid, and MOTS-C needs it dilute because a strong solution can gel.

Yes, every MOTS-C batch is independently lab-tested before it is supplied in Australia, with mass spectrometry used to check its identity. The mass has to match a sixteen-amino-acid chain, since a chain missing even one amino acid would weigh something different. No salt form is published, because it hasn't been confirmed for this material. No matching certificate is currently published for this product and strength.

MOTS-C is a peptide, 16 amino acids long, that is coded by the DNA inside mitochondria, the part of the cell that makes most of its energy, rather than by the nucleus. Almost every other peptide in a cell is coded by DNA in the nucleus, which makes MOTS-C unusual. Researchers first described it in 2015. Australian Research Peptides supplies it as a freeze-dried powder, for laboratory work only.

Exact strength, quantity and listing fit

Per milligram, MOTS-C 10 mg works out to about $9.00 — $89.99 across 10 mg. The 40 mg MOTS-C vial works out to about $3.75 a milligram.

The 10 mg MOTS-C vial costs more per milligram because the costs of supplying one vial, its glass, seal, label and packing, are the same at ten milligrams as at forty. Spread over a quarter of the peptide, those fixed costs weigh more on each milligram. The per-milligram answer on this page gives the live rate for both strengths.

Four 10 mg MOTS-C vials hold the same forty milligrams as one 40 mg vial, and they are the better order only when vials need opening one at a time, with the rest kept sealed and dry. The cost is four lot numbers and four separate mixes; one 40 mg vial is a single lot, and the price answers on this page show it costs less per milligram.

MOTS-C from Australian Research Peptides comes in two strengths, a 10 mg vial and a 40 mg vial, and each figure is the amount of freeze-dried powder sealed in the glass, not a concentration or a purity level. Both vials hold the same sixteen amino acids in the same order; the 40 mg simply holds four times as much, and each strength has its own page and stock code.

Live price, stock and Australian buying

MOTS-C 10 mg costs $89.99 a vial (stock code 16172) at Australian Research Peptides, and two 10 mg MOTS-C vials come to $179.98.

Not on its own. MOTS-C 10 mg is $89.99, $109.01 under $199. MOTS-C clears it with three 10 mg vials. MOTS-C's 40 mg vial falls short too.

$102.98 delivered in Australia. MOTS-C 10 mg is $89.99, plus $12.99 for 16172 by Standard tracked post. Express Post makes 16172 $106.98.

Four vials of MOTS-C. At $89.99 each, four 10 mg vials make $359.96 — past $299, so 16172 ships free by Express Post, costing $359.96.

No, Chemist Warehouse does not stock MOTS-C, and neither does any pharmacy in any market, because this mitochondrial-derived peptide is not registered as a medicine anywhere in the world. That rules out pharmacy supply everywhere, not just in Australia, and there is no prescription version either, because a prescription needs a registered product behind it. Australian Research Peptides lists MOTS-C in 10 mg and 40 mg research vials.

Reconstitution and concentration calculations

Australian Research Peptides publishes no fill volume for 16172, so the amount is a decision for the work rather than one the listing sets. 16172 is 10 mg of dry MOTS-C: what the diluent changes is the solution, never the 10 mg sealed in the glass.

Once mixed, reconstituted MOTS-C keeps for up to twelve weeks in a 2–8 °C fridge, according to the Australian Research Peptides storage panel. That window applies only to the solution, since a sealed dry vial has its own separate rows on the same panel. MOTS-C contains two methionines and a tryptophan, which oxidise easily, so it has more to lose to air and light than a shorter chain. Keep it in the dark, and split it into portions rather than going into one vial again and again.

MOTS-C is normally dissolved in an aqueous (water-based) diluent for laboratory work, which turns the dry powder in the vial into a liquid that can be measured with a pipette. The vial holds only dry powder, with no water or carrier added, and the amount of liquid added sets the concentration.

MOTS-C mixed too concentrated can set to a gel in the fridge, sometimes days later, because in a strong solution its chains link up with each other. Other peptides beside it in the same fridge can stay liquid. A gelled vial is no longer an even solution, so it shouldn't be used. Don't mix MOTS-C too strong: use more bacteriostatic water than you would for most peptides, so the solution stays weaker.

Product identity and research background

MOTS-C stands for mitochondrial open reading frame of the 12S ribosomal RNA type-c, a name that describes where it sits in the genome rather than what it is chemically. An open reading frame is a stretch of genetic code that can be read as instructions for making a peptide, and MOTS-C is classed as a mitochondrial-derived peptide.

MOTS-C is studied for its action on AMPK, a switch that cells turn on when they run short of energy, and the findings so far come from cells and from mice. Lee's 2015 Cell Metabolism report describes it blocking part of the folate pathway, which builds up a molecule called AICAR, and AICAR switches AMPK on. Kim 2018, in the same journal, found that under metabolic stress the peptide also moves into the cell nucleus within about thirty minutes. There it binds antioxidant response elements, stretches of DNA that switch stress-response genes on, and changes how strongly those genes are read.

A MOTS-C vial holds freeze-dried MOTS-C peptide and nothing else, a white to off-white solid that is all peptide rather than peptide mixed through a filler. The glass is sealed under a tamper-evident cap. Nothing is dissolved, blended or divided before dispatch, and the seal stays closed until a laboratory opens it.

No pharmacokinetic profile has been published for MOTS-C, meaning no study has measured how fast it is absorbed, spread through the body or cleared. Santhanam's 2026 rat-heart paper in Naunyn-Schmiedeberg's Archives of Pharmacology ends by calling for pharmacokinetic studies, which confirms that none exist yet. Australian Research Peptides publishes no clearance figure and won't estimate one. What it does publish for MOTS-C is a certificate of analysis for each strength that has one, and the CoA library shows which strengths those are.

MOTS-C is a chain of 16 amino acids, and the sequence that PubChem records for it under CID 146675088 runs Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg. Gao's 2023 review in Metabolites reports that the first eleven positions are highly conserved across species. Residue is the technical word for one amino-acid unit in a chain, so sixteen residues and sixteen amino acids mean the same thing. Every Australian Research Peptides MOTS-C vial holds this same chain.

The published literature records nothing after MOTS-C exposure ends, because no study has looked at what happens once exposure stops. Research on this mitochondrial peptide is only about a decade old, mostly in mice and cultured cells, and everything was measured during the experiment itself. Nothing has been documented either way, and the honest answer is that the question has never been studied.

No, Australian Research Peptides does not supply MOTS-C as a tablet, capsule or nasal spray, and lists it only as a freeze-dried powder in a sealed glass vial. The published research on MOTS-C comes from cell culture and animal models, not from oral or nasal preparations. No regulator anywhere has approved a MOTS-C product in any form, so there is no approved tablet either. A pre-mixed product also uses up part of its stability window before it is even posted, while a sealed freeze-dried vial only starts that window when the researcher mixes it.

Storage, condition and testing

Yes, it is normal for a MOTS-C vial to look almost empty, because even the 40 mg vial holds only a small pale cake of powder rather than a vial full of it. Dried peptide takes up very little room, and no filler or carrier is added, which is exactly why there is so little to see.

MOTS-C should be stored dry and tightly sealed below -15 °C, and colder still for the long term, in line with Bachem's handling guidance for freeze-dried peptides. This matters because MOTS-C contains two methionines and a tryptophan, amino acids that oxidise more easily than most. Cold glass draws moisture from the air, so let the sealed vial warm up in a desiccator before opening it. Solutions don't keep well, so freeze them in single-use portions.

MOTS-C usually looks cloudy after mixing because of air, since swirling or turning the vial over repeatedly pushes bubbles through the liquid that scatter light just like real cloudiness. The bubbles clear once the vial is left alone, and a 40 mg vial holds a lot of powder, so it takes longer to clear than a smaller fill. Anything still opaque after that, or grit that won't dissolve, is not just bubbles.

Australian Research Peptides publishes storage conditions for MOTS-C rather than an expiry date, so this page gives no shelf-life figure for a sealed vial, and none should be borrowed from elsewhere. The storage panel gives the sealed dry vial two options, frozen for the long term or refrigerated for a few months, and gives a mixed solution a shorter window of its own. How long a freeze-dried vial lasts depends on how it has actually been kept, which is why the conditions are what get published.

Delivery, payment and access questions

Australian Research Peptides sells MOTS-C to laboratories and researchers in Australia for in vitro research purposes only, not as a medicine, and it is not supplied for use in people or animals. No Australian Research Peptides material describes such use. MOTS-C is a research compound, not an approved treatment, and it has not been assessed as one. Anyone buying it is responsible for the rules that apply to their own work.

No, MOTS-C is not FDA approved, and no drug regulator in any country has approved it, so no registered medicine contains it. Lee and colleagues only described this mitochondrial-encoded peptide in 2015, so its research record is short and almost entirely preclinical, and none of it has been submitted for review. A vial of MOTS-C is unregistered material intended for laboratory experiments.

Yes, MOTS-C is banned in sport at all times, both in and out of competition, under the World Anti-Doping Agency's prohibited list. Unusually, the list names it in full, as mitochondrial open reading frame of the 12S rRNA-c, and groups it with AICAR as an AMPK activator among the metabolic modulators. Sport Integrity Australia oversees testing for Australian athletes.