Buy Semax in Australia
Semax is a seven-amino-acid chain supplied in Australia by Australian Research Peptides in 10 mg and 30 mg vials, and it lifts the brain's supply of BDNF and nerve growth factor, the proteins that keep neurons alive and hold their connections together. It also stirs serotonin activity in the striatum — a combination tied to sharper learning and to protecting nerve tissue after a stroke. The chain is a laboratory extension of an adrenocorticotropic hormone fragment, and each vial holds it dried to a solid under seal. For in vitro research purposes only.
Nootropic Peptides · Lyophilised Powder · Batch-tested · SKU ARP-SEMAX-10
$65.99
2+ vials: 5% off — applied automatically in the cart
Presentation
10 mg per vial
Grade
High-Purity Research Grade
Form
Lyophilised Powder
Category
Nootropic Peptides
Currently out of stock — stocked lines dispatch same business day before 12pm AEST, Mon–Fri
Tracked shipping Australia-wide ·typically 1–2 business days to most areas by Express Post · free post over $199, free Express over $299
For in vitro research purposes only. Not for human consumption. Not for animal consumption. This product is not a drug, food, cosmetic, or dietary supplement. Any amounts shown are reported from published studies, with the species or trial population named. ARP gives no dosing, medical or therapeutic guidance of its own.
Semax · 10 mg
$65.99
Frequently Bought Together
About Semax
Semax is studied for neuroprotection, which means research into keeping nerve cells alive after injury. Rats given Semax after an induced stroke showed stronger transcription of the genes for nerve growth factor, BDNF and their receptors. A second rat study measured less of the active stress enzyme JNK and more active CREB, a switch that turns genes on. Mice showed a 25 percent rise in a serotonin breakdown product in the striatum after two hours. All of that is animal data.
Semax is a heptapeptide, which simply means a chain of seven amino acids. Written out it is Met-Glu-His-Phe-Pro-Gly-Pro, or MEHFPGP in single-letter code. The opening four are positions 4 to 7 of adrenocorticotropic hormone. The closing three, proline-glycine-proline, are synthetic, and the hormone does not carry them. Published papers file the compound both as ACTH(4-7)PGP and as an analogue of ACTH(4-10). Either way it is an analogue, so nothing proven about the hormone transfers to Semax.
Australian Research Peptides lists Semax under Nootropic Peptides, in a 10 mg and a 30 mg vial. Both hold the same chain and differ only in how much powder was weighed in. ARP checks every batch two ways before selling it. HPLC measures what share of the sample runs as one peak, and mass spectrometry confirms the mass matches a seven-amino-acid chain rather than the four-amino-acid fragment alone. Each batch has a certificate of analysis, sent on request.
Content reviewed
Further reading: Semax vs Selank: What Is the Difference?
Semax specifications, storage and shipping
- Compound: Semax
- Also known as: Semax (Met-Glu-His-Phe-Pro-Gly-Pro; ACTH(4-7) with Pro-Gly-Pro)
- Class: Synthetic heptapeptide; ACTH(4-7) analogue
- Appearance: White to off-white lyophilised powder
- Sizes & SKUs: 10 mg (ARP-SEMAX-10), 30 mg (ARP-SEMAX-30)
- Presentation: sealed glass vial
- Form: Lyophilised Powder
- Grade: High-purity research grade
- Purity verification: HPLC-assayed on every batch to a minimum of 99% purity — the measured result for your batch is stated on its Certificate of Analysis
- Identity confirmation: Mass spectrometry
- Classification: In vitro research purposes only — laboratory reference material
- Lyophilised — long term
- −20 °C to −80 °C — long-term storage
- Lyophilised — short term
- 2–8 °C — refrigerated, for a few months
- Reconstituted
- 2–8 °C — use within 8–12 weeks
Every batch undergoes HPLC purity analysis and mass-spectrometry identity confirmation. No laboratory report is published for this line yet. The COA library lists every product and strength, and says which reports are available.
This line is currently out of stock. Stocked lines ordered before 12pm AEST on a business day are dispatched the same day with tracked, discreet shipping. Standard delivery within Australia typically takes 2–5 business days. See Shipping & Delivery for details, and follow your parcel on the Track Order page.
For in vitro research purposes only. Not for human consumption. Not for animal consumption. Not a drug, food, cosmetic, or dietary supplement. No therapeutic or medical claims are made.
Questions about Semax
This question guide from Australian Research Peptides covers Semax in Australia: what the listing contains, live buying and delivery questions, research context, handling, testing and comparisons. Start with the quick answers, then open the topic group that matches your search.
Buying, price and availability
Semax, indexed as ACTH 4-7, is sold in Australia by Australian Research Peptides Pty Ltd, which posts every parcel from Sydney — no border crossing, no customs queue. Stock code SEMAX runs in two vial sizes, 10 mg and 30 mg, within the Nootropic Peptides range. The shelf is empty for now, and a returning batch picks the 12pm AEST weekday cut-off back up; Express delivery reaches all states and territories. Payment is PayID or bank transfer.
A Semax restock alert from Australian Research Peptides is a notification, not a reservation. It reports that stock has landed; it holds no vial, and returning stock is sold first come, first served. Acting on the email promptly matters most where a strength returns in small quantities.
Semax reaches Australian labs through Australian Research Peptides, a Sydney company posting domestically, so nothing is imported to order or held at customs. The Nootropic Peptides listing covers 10mg and 30mg vials under stock code SEMAX, and searches for ACTH 4-7, MEHFPGP or a mistyped name arrive at the same ARP record. Express Post reaches all states and territories, tracked standard alongside it, and the same-day rule for anything in by 12pm AEST applies again from the next batch. HPLC testing precedes release, and the CoA library marks each strength as published or still to come. PayID or bank transfer.
Semax is priced per vial by Australian Research Peptides, with a separate Australian-dollar figure for the 10 mg and the 30 mg. Neither figure is fixed in writing; both are read from the current catalogue at the moment they are quoted. Semax holds the HPLC Verified grade, and only lines with that grade attract the automatic multi-vial discount.
Semax is listed by Australian Research Peptides in two vial sizes, 10 mg and 30 mg, dispatched from Sydney. The business banks by PayID and bank transfer alone, so no card or wallet is involved anywhere in the transaction. Bank details reach the buyer with the order confirmation, and stock is reserved while the transfer clears.
Semax is available from Australian Research Peptides and not from Chemist Warehouse, which cannot sell it. Semax is a registered medicine in Russia and in no other market, so there is no Australian registration for a pharmacist here to dispense against. ARP supplies it as a research compound in two vial sizes, under Nootropic Peptides.
Identity, names and exact format
Semax is a synthetic peptide of seven amino acids, made by attaching a three-residue tail to a four-residue fragment of adrenocorticotropic hormone — the fragment chosen because it carries none of the parent hormone's hormonal activity. It was developed in Moscow and is studied in cognition and neuroprotection research, largely in Russian-language literature.
Australian Research Peptides supplies Semax as one freeze-dried solid in a sealed vial, not as a liquid nasal product. That solid is the chain MEHFPGP, at the milligram weight printed on the label. The powder runs white to off-white inside sealed, tamper-evident glass. There is no filler, no carrier, no second peptide and no liquid. Four of the seven amino acids reproduce part of adrenocorticotropic hormone, and the closing proline-glycine-proline is added in the lab.
Semax is built from seven amino acids in one chain, which makes it a heptapeptide. In order they are Met-Glu-His-Phe-Pro-Gly-Pro, shortened to MEHFPGP. Met-Glu-His-Phe is a stretch of adrenocorticotropic hormone, positions four through seven. The last three are a synthetic addition the hormone itself does not have. The count of seven belongs to Semax itself, so both vial sizes contain the identical chain.
Semax is also known as ACTH(4-7)PGP, as MEHFPGP in single-letter code, and by its written sequence Met-Glu-His-Phe-Pro-Gly-Pro; some papers file it as an analogue of ACTH(4-10). Replacing the last three residues with Pro-Gly-Pro is what removes the corticotropic activity, so it is an analogue rather than a piece of ACTH itself. N-Acetyl Semax and the amidated version are related molecules with their own database records, not alternative names. Whichever term you typed, the vial ships from Australian Research Peptides, warehoused locally and HPLC-tested, with the CoA library showing where a certificate is already published.
Research context and evidence
Published work on Semax centres on gene expression in brain tissue. Dmitrieva 2010 found Semax raised transcription of the genes for BDNF, nerve growth factor and their Trk receptors in rats. Those proteins keep neurons alive and maintain their connections. Dolotov 2006 gave rats a single intranasal dose of 50 micrograms per kilogram and saw hippocampal BDNF protein rise 1.4-fold. Sudarkina 2021 measured more active CREB, a gene switch, in damaged tissue.
Research on Semax is almost entirely in animals, and mostly about the brain after injury. Dmitrieva 2010 found that in a rat stroke model Semax activated transcription of Bdnf, Ngf and Nt-3 and their receptors. Sudarkina 2021 reported active JNK down more than 1.5-fold and Fos mRNA down 2.6-fold in ischaemic rat tissue. Eremin 2005 measured 5-HIAA, a serotonin breakdown product, up 25 percent in mouse striatum within two hours.
Animal studies gave Semax into the nose or by injection into the abdomen. Dolotov 2006 used one intranasal dose of 50 micrograms per kilogram in rats. Sudarkina 2021 and Medvedeva 2014 both injected Wistar rats with 100 micrograms per kilogram, repeated over the first hours after an induced stroke. Eremin 2005 used 0.15 milligrams per kilogram by injection in C57BL mice. Every amount quoted for Semax comes from an animal study.
Semax survives in blood only briefly, though no clean half-life figure has been printed. Potaman's 1991 study in Biochemical and Biophysical Research Communications followed it through rat serum by chromatography, finding aminopeptidase stripping the first two residues away. The intermediates accumulated in comparable amounts, and those authors argued such fragments may carry part of the parent's activity, so the original chain disappearing is not the end of the account.
Semax has more human data behind it than most research peptides, because it has been a registered product in Russia for decades and its literature includes clinical studies in stroke and cognitive settings. That literature is largely Russian-language and has not been replicated in large Western trials, which is the main reason it remains unfamiliar elsewhere.
Semax's published studies sampled effects over hours to days rather than months, and the acute stroke work administered it over a defined short course. There is no long-run controlled trial establishing what happens over weeks of continuous use, so a timescale in months is not something the evidence supports either way.
Semax has decades of Russian clinical use behind it, and that literature describes courses with a defined endpoint rather than indefinite use, yet published observation after a course concludes is thin. No withdrawal syndrome is reported in it. Since that record has never been assessed outside Russia and large independent trials have not repeated it, it makes weak ground for confident statements about stopping.
Semax's registered form in Russia is an intranasal solution, and its clinical record describes it as well tolerated with local nasal irritation the main issue noted. No Western regulator has reviewed that record, and none of it describes the lyophilised research powder Australian Research Peptides supplies or any route other than nasal.
A Semax rat study recorded a behavioural change alongside its brain measurements. Dolotov 2006 used conditioned avoidance, a learning test where an animal learns to dodge a signalled unpleasant stimulus. Treated rats produced more avoidance reactions than controls. The authors read that beside the rise in hippocampal BDNF. This is a result in rats, and nothing follows from it about people.
Handling, storage and measurements
Semax has no set volume, because the water added sets the strength. Peptide mass divided by liquid volume gives the concentration. At 2 mL, the 10 mg vial sits at 5 mg/mL, or 5,000 micrograms per millilitre. Halve the water to 1 mL and it doubles to 10 mg/mL. The 30 mg vial reaches that same 10 mg/mL at 3 mL. Australian Research Peptides' calculator guide in Articles covers other volumes.
Semax comes in two quantities and they look markedly different. Ten milligrams leaves a faint dusting easily read as an empty container; thirty milligrams is three times as much solid and forms a properly visible cake. Neither holds a bulking agent, so what sits inside the glass is peptide alone. Comparing the two strengths explains most confusion about the smaller one.
Store the sealed Semax vial frozen, dry and out of the light. GenScript flags cysteine, methionine and tryptophan as prone to oxidation, and Semax opens with a methionine, which is why light and air matter. Bachem keeps freeze-dried peptides below minus 15 degrees Celsius in a closed container, and GenScript's own figure is minus 20, away from bright light. Warm a frozen vial fully before you break the seal, so moisture does not condense inside. Peptide in solution is far less stable than the dry powder.
Reconstituting Semax means adding sterile liquid to the dry vial and letting the powder dissolve. Bring the glass up to room temperature first. Tilt it, and let the liquid enter against the side rather than falling onto the solid. Swirl gently or roll the vial. Do not shake it. Seven amino acids is a short chain, so Semax normally dissolves without heat or organic solvent.
Semax in solution is refrigerated at 2 to 8 degrees and given a life of eight weeks to twelve by Australian Research Peptides' published condition. Semax opens on a methionine — MEHFPGP places the most oxidation-prone residue first, at an unblocked N-terminus — so light and dissolved air deserve as much attention as the calendar. The 30 mg vial is likelier to outlast that window.
Most cloudy Semax reports come down to bubbles worked in during mixing, and they lift out within minutes of the vial being set down. The thirty-milligram strength dissolves more slowly than the ten, having three times as much material to take up, so patience beats extra agitation. Once warmed and rested a proper preparation is clear; lasting milkiness or floating specks are not normal.
Semax needs bacteriostatic water because the vial contains dry peptide and nothing wet. Australian Research Peptides keeps that water in Lab Supplies under its own listing, never bundled into the Semax entry. Diluent is the standard term for whatever a dry compound dissolves into. Semax comes in two vial sizes, both equally dry, so each needs its own.
The Semax strength choice changes the answer threefold: at 300 mcg a draw, the 10 mg vial gives roughly 33 and the 30 mg gives 100. Semax is used at smaller amounts than most research peptides, which is why the 30 mg vial lasts a long time.
Testing and batch documents
Semax is analysed two ways before supply — HPLC first, then mass spectrometry. HPLC separates the sample and reports what fraction runs as the main peak. Mass spectrometry reads the molecular mass and compares it against what the sequence predicts. For Semax that second check matters, because it separates a seven-amino-acid chain from the shorter ACTH(4-7) fragment it opens with. No matching certificate is currently published for this product at any strength.
Testing on Semax settles which of three similarly named molecules is in the vial. Plain Semax, N-Acetyl Semax and the amidated form have different molecular formulas, so each has a different mass. Mass spectrometry reads that mass. HPLC reports what share of the material runs as one peak. Neither method says anything about sterility, endotoxin levels, or use in people or animals.
Ordering, payment and Australian delivery
A Semax payment can come from an account in a different name to the order — a partner's account, a joint account — provided the order reference is in the description, because it is the reference rather than the name that does the matching. Without it, a mismatched name is exactly the case that cannot be resolved automatically.
The two Semax sizes answer this differently. Two of the 30 mg vials pass the free Standard tracked post mark, while the 10 mg vial takes four. Express Post is waived a step higher and needs a third of the larger vial. Semax and Selank are commonly ordered together, and that combination usually clears the standard threshold on its own.
Semax spends 2–5 business days in the standard tracked post network, or 1–2 in the Express Post one for most addresses. A delivery address can be corrected up until the parcel is packed, so tell support as soon as you spot a typo and they will fix it before it goes out. Once a tracking number is issued the address is with the carrier.
A 30 mg Semax vial takes three times the diluent of a 10 mg one for the same concentration, so the water size follows the strength you buy rather than the product. Note also that Australian Research Peptides supplies Semax as powder for reconstitution, not as the intranasal solution its registered form is sold as. Syringes are not included.
Access, approval and sport questions
Semax is sold in Australia as a laboratory research chemical, and Australian Research Peptides supplies it on that basis only. ARP makes no medical claim for Semax anywhere. Australia sorts medicines and poisons into schedules under the Poisons Standard, administered by the TGA. Anything to do with use in a person sits outside what ARP supplies Semax for.
Semax has never been approved in the United States. It is approved somewhere, however: Russia's health ministry registered it as a medicine in 1994, in an intranasal form. A registration granted in one country is not a worldwide licence, and no Western agency has assessed the Russian-language clinical record standing behind it. Freeze-dried research powder is not that registered product in any case.
Semax has no listing of its own in any prohibited category. Whether the residual S0 heading reaches it turns on one point: Russia's health ministry registered Semax as a medicine in 1994, and S0 excludes anything a government regulator has approved somewhere. Whether an anti-doping panel accepts a Russian registration is untested, so Australian athletes should ask Sport Integrity Australia.
Semax is sold as a registered medicine in Russia and has never been registered in Australia, so a personal import runs straight into the Personal Importation Scheme's conditions. Those limit quantity, require the goods be for the importer's own use, and do not waive the TGA's controls on unapproved goods. None of it applies to an Australian Research Peptides order, which is packed and posted inside Australia.